Biography
I am Professor of Innate Immunity at the Departments of Medicine and Veterinary Medicine in the University of Cambridge. I study innate immune cell signalling in response to Pathogen Associated Molecular Pattern Receptor (PRR) activation during bacterial infection using innovative, multi-disciplinary approaches (collaborating with mathematicians, physicists and physical chemists) to answer fundamental questions about host-pathogen interactions and how to modify them therapeutically. I have also applied these innovative approaches to study PRR-induced inflammatory signalling in chronic inflammatory diseases such as Alzheimer’s and Parkinson’s. Predominantly my research is cell biology based (using knock out mouse models to test concepts in vivo).